Crescendo Care

CRESCENDO CARE SRL has developed a high-tech diagnostic hub and know-how for analysis services using tandem spectrometry coupled with ultraperformance liquid chromatography (UPLC-MS/MS) and IVDR-compliant instrumentation.

Our added value:

• we measure the analytes in their natural state of oxidation and reduction, givingthus an exact snapshot of the matrix characteristics (plasma,cells, mitochondria etc…) at the time of sampling even for oxidoreductively labile metabolites;
• we quantify analytical species in the oxidized and reduced state by methods not nowadays otherwise available in the market. Some samples: Argininosuccinic acid anhydride Ist, Argininosuccinic acid anhydride 2nd, Glutathione disulphide (or oxidized glutathione), reduced Glutathione, Selenomethionine, Selenocysteine, Tetrahydrobiopterine, Dihydrobiopterine, Biopterin, Lactic acid, Pyruvic acid, Methionine sulfone, Methionine sulfoxide.
• we perform analytical quantifications not only in standard matrices (blood and urine), but in a wide number of matrices, including cellular and subcellular (red blood cells, white blood cells, mitochondria). The metabolite assay or certain drugs can be performed at the intracellular or organelle levellike mitochondria.

Our services are ideal for quantification of extensive analytical panels and on high number of biological samples; we collaborate with research centers, companies, BioBanks.